Status:
COMPLETED
Randomized Trial of Pulsatile vs Non Pulsatile Perfusion on Short Term Changes in Kidney Function Using an Intra-Aortic Ballooon Pump During Cardioplegic Arrest in Patients Undergoing Myocardial Reperfusion
Lead Sponsor:
University of Catanzaro
Conditions:
Aortocoronary Bypass
Eligibility:
All Genders
18-75 years
Phase:
PHASE4
Brief Summary
Linear flow during cardiopulmonary bypass (CPB) frequently induces renal damage. We will evaluate whether automatic intra-aortic balloon pump (IABP) induce pulsatile perfusion preserves renal functio...
Detailed Description
Linear flow during cardiopulmonary bypass (CPB) frequently induces renal damage. We will evaluate whether automatic intra-aortic balloon pump (IABP) induced pulsatile perfusion preserves renal functi...
Eligibility Criteria
Inclusion
- Patients undergoing isolated primary high-risk coronary artery bypass grafting for severe left main stem disease (70% narrowing) or left-main equivalent three-vessels coronary disease
Exclusion
- Patients older than 75 years
- With kidney disease ≥ Stage 4 (GFR 15 - 29 ml/min/1.73 m2)
- With other splanchnic organ comorbidities (liver or mesenteric impairment, abdominal aortic aneurysm, abdominal arteries vasculopathy)
- Severe autoimmune disease.
Key Trial Info
Start Date :
Trial Type :
INTERVENTIONAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00454428
Last Update
March 30 2007
Active Locations (1)
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1
Cardiac Surgery and Nephrology
Catanzaro, Catanzaro, Italy, 88100