Status:

COMPLETED

The Effect of Fish Oil Supplementation on Endothelial Function, Heart Rate Variability and Intimal Media Thickness of Patients With Coronary Artery Disease

Lead Sponsor:

Olive View-UCLA Education & Research Institute

Collaborating Sponsors:

Reliant Pharmaceuticals

Conditions:

Coronary Artery Disease

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

The purpose of this study is to investigate whether there is a difference in endothelial function, heart rate variability and carotid intimal media thickness in patients with coronary artery disease w...

Eligibility Criteria

Inclusion

  • Established coronary artery disease as determined by coronary angiography within the last 5 years demonstrating at least 50% stenosis in one of the major coronary vessels
  • Age \>18 and \<75.

Exclusion

  • Baseline fish oil intake ≥1g/day or fish intake \>100g/day
  • Need for urgent or emergent CABG
  • Contraindication for plavix, aspirin or statin
  • Gastrointestinal malabsorption syndrome
  • Pregnancy
  • Oral contraceptive use
  • Ejection fraction \<40%
  • Underlying atrial or ventricular arrhythmia
  • History of rheumatoid arthritis

Key Trial Info

Start Date :

August 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2008

Estimated Enrollment :

71 Patients enrolled

Trial Details

Trial ID

NCT00454493

Start Date

August 1 2006

End Date

December 1 2008

Last Update

March 13 2019

Active Locations (1)

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1

OV-UCLA Medical Center

Sylmar, California, United States, 91342