Status:

COMPLETED

Late-Onset Treatment Study Extension Protocol

Lead Sponsor:

Genzyme, a Sanofi Company

Conditions:

Pompe Disease (Late-Onset)

Glycogen Storage Disease Type II (GSD-II)

Eligibility:

All Genders

8+ years

Phase:

PHASE4

Brief Summary

Pompe disease (also known as glycogen storage disease Type II) is caused by a deficiency of a critical enzyme in the body called acid alpha-glucosidase (GAA). Normally, GAA is used by the body's cells...

Eligibility Criteria

Inclusion

  • Patient must have completed protocol AGLU02704 (NCT00158600)
  • Patient must provide signed, informed consent prior to performing any study-related procedures
  • Patient (and patient's legal guardian if patient is under 18 years of age) must have the ability to comply with the clinical protocol
  • A female patient of childbearing potential must have a negative pregnancy test at Baseline. (note: all female patients of childbearing potential and sexually mature males must use a medically accepted method of contraception throughout the study.)

Exclusion

  • The patient has a medical condition, serious intercurrent illness, or other extenuating circumstance that, in the opinion of the Investigator, would preclude treatment with alglucosidase alfa.

Key Trial Info

Start Date :

March 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2008

Estimated Enrollment :

81 Patients enrolled

Trial Details

Trial ID

NCT00455195

Start Date

March 1 2007

End Date

November 1 2008

Last Update

March 7 2014

Active Locations (31)

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Page 1 of 8 (31 locations)

1

Anchorage, Alaska, United States

2

Phoenix, Arizona, United States

3

Beverly Hills, California, United States

4

San Diego, California, United States