Status:
COMPLETED
Home Treatment of Patients With Pulmonary Embolism Based on Pro-Brain Natriuretic Peptide (BNP) Levels
Lead Sponsor:
St. Antonius Hospital
Collaborating Sponsors:
Diakonessenhuis, Utrecht
Groene Hart Ziekenhuis
Conditions:
Pulmonary Embolism
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The aim of this study is to investigate the safety of treatment of pulmonary embolism in an outpatient setting based on normal pro-BNP levels. The mortality rate and the incidence of hemodynamic insta...
Detailed Description
Pulmonary embolism is a major health problem. Because of risk for early hemodynamic instability and mortality, all patients with a recently diagnosed pulmonary embolism are treated in hospital. The cl...
Eligibility Criteria
Inclusion
- outpatient with a pulmonary embolism, confirmed by locally approved guidelines
- aged 18 years and above
- written informed consent
Exclusion
- hemodynamic or respiratory instability defined as one of the following; hypotension RR systolic\< 90 mmHg,pulse rate\> 100 bpm, need for oxygen therapy to maintain oxygen saturation above 90 %, collapse
- illness unrelated to PE for which the patient would require hospitalization
- pain requiring intravenous narcotics
- thrombolysis
- active bleeding or thrombopathy
- pregnancy
- in hospital patients
- physical or psychiatric inability for home treatment
- no support system at home renal insufficiency
Key Trial Info
Start Date :
December 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2009
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT00455819
Start Date
December 1 2006
End Date
March 1 2009
Last Update
March 31 2009
Active Locations (2)
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1
St Antonius Hospital
Nieuwegein, Netherlands, 3430 EM
2
Mesos Medical Centre
Utrecht, Netherlands, 3503 RP