Status:
UNKNOWN
Baselines in Reproductive Disorders
Lead Sponsor:
Massachusetts General Hospital
Collaborating Sponsors:
National Institutes of Health (NIH)
Conditions:
Amenorrhea
Hypogonadotropic Hypogonadism
Eligibility:
FEMALE
16-45 years
Phase:
NA
Brief Summary
The purpose of the study is to explore the way in which gonadotropins (pituitary hormones) are released into the body. The knowledge acquired in this study will be used for the diagnosis and treatment...
Detailed Description
Normal reproductive cycles in women require the integrated function of the hypothalamus, pituitary and ovaries. The hypothalamic component of the reproductive system can be assessed directly in lower ...
Eligibility Criteria
Inclusion
- Healthy women between the ages of 16-45 years
- Negative pregnancy test
- On no gonadal steroid preparations for at least 3 months, with the exception of the idiopathic hypogonadotropic hypogonadism (IHH) group, they should be off gonadal steroid for at least 4 weeks
- The following test will be performed if they had not been done in the last 2 months
- Normal blood count
- Normal thyroid function test
Exclusion
- Hemoglobin levels less than 11 gm/dL
- Positive pregnancy test
- Abnormal thyroid function
- Abnormal MRI (IHH)
Key Trial Info
Start Date :
September 1 1999
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2020
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT00456274
Start Date
September 1 1999
End Date
September 1 2020
Last Update
August 4 2014
Active Locations (1)
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1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114