Status:
RECRUITING
Identifying Genetic Characteristics That Increase Risk of Primary Graft Dysfunction Following Lung Transplantation
Lead Sponsor:
University of Pennsylvania
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Columbia University
Conditions:
Primary Graft Dysfunction
Lung Transplantation
Eligibility:
All Genders
15-65 years
Brief Summary
Primary graft dysfunction (PGD) is a severe lung injury that can occur in the days following lung transplant surgery. The purpose of this study is to identify genetic factors that may put someone at r...
Detailed Description
PGD is a severe complication that affects up to 25% of lung transplant patients following surgery. Pulmonary edema, which is an abnormal build-up of fluid in the lungs, and hypoxemia, which is low blo...
Eligibility Criteria
Inclusion
- Undergoing lung transplant surgery
Exclusion
- \- Individuals undergoing multi-organ transplantation except heart/lung transplants
Key Trial Info
Start Date :
February 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2026
Estimated Enrollment :
1150 Patients enrolled
Trial Details
Trial ID
NCT00457847
Start Date
February 1 2007
End Date
June 1 2026
Last Update
July 16 2025
Active Locations (1)
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1
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104