Status:
COMPLETED
Isotonic Versus Hypotonic Fluid for Maintenance IV Therapy
Lead Sponsor:
McGill University Health Centre/Research Institute of the McGill University Health Centre
Conditions:
Gastroenteritis
Bronchiolitis
Eligibility:
All Genders
1-18 years
Phase:
PHASE3
Brief Summary
Hyponatremia associated with administration of hypotonic intravenous (IV) fluids may have serious complications. It has recently been suggested that isotonic saline may be a more appropriate choice of...
Eligibility Criteria
Inclusion
- 1 month to 18 years of age
- Require IV fluids for at least 8 hr.
- Baseline serum sodium \>=136 mmol/L \& \<=145 mmol/L
Exclusion
- Baseline serum sodium concentration less than 136 mmol/L or greater than 145 mmol/L
- Renal disease, a history of cardiac dysfunction or evidence of cardiac dysfunction, pre-existing hypertension, diuretic use, edema, or known adrenal dysfunction
- Acute neurological illness such as meningitis or encephalitis
- Severe chronic neurological illnesses (uncontrolled seizure disorders, severe developmental delay)
Key Trial Info
Start Date :
January 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2008
Estimated Enrollment :
38 Patients enrolled
Trial Details
Trial ID
NCT00457873
Start Date
January 1 2007
End Date
April 1 2008
Last Update
April 12 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Montreal Children's Hospital
Montreal, Quebec, Canada, H3H 1P3