Status:
COMPLETED
Phenylephrine in Spinal Anesthesia in Preeclamptic Patients
Lead Sponsor:
Northwestern University
Conditions:
Preeclampsia
Hypotension
Eligibility:
FEMALE
18-60 years
Phase:
NA
Brief Summary
Hypotension remains a common clinical problem after induction of spinal anesthesia for cesarean delivery. Maternal hypotension has been associated with considerable morbidity (maternal nausea and vomi...
Detailed Description
The study will be approved by the Northwestern University Institutional Review Board. Eligible women admitted to the Labor and Delivery Unit of Prentice Women's Hospital will be approached for study p...
Eligibility Criteria
Inclusion
- ASA PS II - III women
- 18 years old and older
- scheduled for cesarean delivery (no trial of labor)
- eligible for spinal anesthesia
- diagnosis of preeclampsia
Exclusion
- patients with failed trial of labor
- preexisting hypertension
- body mass index (BMI) ≥ 40 kg/m2
- resting heart rate \< 60 bpm
- progression to eclampsia, \> twin gestation
- known fetal anomalies
- contraindications to spinal anesthesia
- emergency procedure or refusal of consent
- failure to achieve a T6 level of anesthesia
- conversion to general anesthesia
Key Trial Info
Start Date :
July 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2016
Estimated Enrollment :
110 Patients enrolled
Trial Details
Trial ID
NCT00458003
Start Date
July 1 2006
End Date
December 1 2016
Last Update
June 2 2022
Active Locations (2)
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1
Northwestern Memorial Hospital
Chicago, Illinois, United States, 60611
2
Northwestern University
Chicago, Illinois, United States, 60611