Status:
COMPLETED
High-Density Lipoprotein (HDL) Treatment Study
Lead Sponsor:
McGill University Health Centre/Research Institute of the McGill University Health Centre
Conditions:
Coronary Arteriosclerosis
Hypoalphalipoproteinemias
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
A low level of plasma high-density lipoprotein (HDL) cholesterol, "the good cholesterol", is the most common lipid abnormality observed in patients with a premature atherosclerotic cardiovascular dise...
Detailed Description
Objective and rationale. We have collected, in the past 15 years, a large group of patients with familial HDL cholesterol deficiency. In approximately 25% of index probands in our family studies, the ...
Eligibility Criteria
Inclusion
- \- HDL deficiency (HDL-cholesterol \< 5th percentile, age and gender-matched)
Exclusion
- Triglycerides ≥ 5 mmol/L
- Diabetes
- Severe obesity (BMI ≥ 30)
- Alcohol intake \> 21 drinks/week
- Untreated disease (thyroid, hepatic or renal)
Key Trial Info
Start Date :
November 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2007
Estimated Enrollment :
19 Patients enrolled
Trial Details
Trial ID
NCT00458055
Start Date
November 1 2006
End Date
September 1 2007
Last Update
June 4 2008
Active Locations (1)
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1
MUHC-Royal Victoria Hospital
Montreal, Quebec, Canada, H3A 1A1