Status:

COMPLETED

Biochemical Markers of Growth Response to Growth Hormone Treatment in Children With Idiopathic Short Stature

Lead Sponsor:

Rabin Medical Center

Collaborating Sponsors:

Pfizer

Conditions:

Idiopathic Short Stature

Eligibility:

All Genders

3-9 years

Phase:

PHASE4

Brief Summary

One arm, open, prospective, intervention study to assess biochemical markers of growth response to Growth Hormone treatment in 20 Children, aged 3-9 years old, with idiopathic short stature. All parti...

Detailed Description

One arm, open prospective intervention study to assess biochemical markers of growth response to Growth Hormone treatment in 20 children, aged 3-9 years old, with idiopathic short stature. Objectives...

Eligibility Criteria

Inclusion

  • Ages 3 to \<9 years
  • Short stature with height \>2.25 Standard Deviation below the mean
  • Prepubertal (Tanner stage I) at commencement of trial
  • Peak Growth Hormone above 10ng/ml in at least one provocative test for Growth Hormone secretion
  • Signing informed consent forms

Exclusion

  • Intra Uterine Growth Retardation
  • Growth retardation associated with malignancy, severe chronic disease, genetic syndromes and endocrine disorders
  • Diabetes
  • Treatment with any medical product which may interfere with Growth Hormone

Key Trial Info

Start Date :

April 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2011

Estimated Enrollment :

21 Patients enrolled

Trial Details

Trial ID

NCT00458263

Start Date

April 1 2006

End Date

May 1 2011

Last Update

January 3 2013

Active Locations (1)

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schneider children medical center of Israel

Petah Tikva, Israel, 49202