Status:
COMPLETED
Functional Neuroanatomy of Emotion Perception, Recognition, Learning, and Memory
Lead Sponsor:
National Institute of Mental Health (NIMH)
Conditions:
Healthy
Eligibility:
All Genders
20-40 years
Brief Summary
This study uses magnetic resonance imaging (MRI) to explore the areas of the brain involved in different types of mental processes, in particular, the brain regions involved in perception, recognition...
Detailed Description
The long-term goals of this study are to understand the neural substrates of aversive Pavlovian conditioning in human subjects. The general approach is to use whole brain functional magnetic resonance...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Normal right-handed volunteers with at least a high school education, age 20 to 40 years, will be recruited to participate in this study.
- EXCLUSION CRITERIA:
- Subjects will be excluded if they have evidence of or a history of learning disability, psychiatric condition, head trauma, seizures or other neurological condition, alcoholism or substance abuse, hypertension, or cardiovascular disease. We will also exclude subjects with vision and/or hearing problems severe enough to interfere with testing. Lab work will be limited to a urine pregnancy test for females. Females with a positive pregnancy test will be excluded from neuroimaging studies. All subjects will be questioned prior to MRI scanning for possible occupational exposure to metal slivers or shavings, which may have become accidentally lodged in the tissues of the head or neck. Those whose history is suggestive of such a problem will be excluded. Subjects with surgical clips or shrapnel in or near the brain or blood vessels, subjects with cochlear implants, subjects with any metallic body in the eye or CNS, and subjects with any form of implant wire or metal device which may concentrate radiofrequency fields will be excluded because of possible risks during MRI scanning.
Exclusion
Key Trial Info
Start Date :
April 5 2007
Trial Type :
OBSERVATIONAL
End Date :
August 31 2009
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT00458432
Start Date
April 5 2007
End Date
August 31 2009
Last Update
July 2 2017
Active Locations (1)
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1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892