Status:
UNKNOWN
PEARL Intervention to Reduce Depression Among Adults With Epilepsy
Lead Sponsor:
University of Washington
Collaborating Sponsors:
Centers for Disease Control and Prevention
Conditions:
Depression
Epilepsy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to test the effectiveness of a home-based depression treatment intervention called "Program to Encourage Active, Rewarding Lives (PEARL)". We hypothesize that over a 12-mo...
Detailed Description
Compared to non-depressed individuals with epilepsy, those with depression have significantly higher rates of suicide, lower social and occupational functioning, decreased quality of life independent ...
Eligibility Criteria
Inclusion
- Home address within 30 miles of Seattle
- Diagnosis of epilepsy (ICD-9 code 345.XX)
- Appointment in the UW REC or Neurology clinic in the past 2 years and currently enrolled in this clinic.
- Current age older than 18 years
- Diagnosis of major depression, minor depression or dysthymia
- Ability to speak/read English
Exclusion
- Alcohol and/or substance abuse/dependence based on a score greater than 1 on 4-item validated CAGE-AID
- Cognitive impairment based on a score less than 3 on a 6-item validated cognitive screen
- Diagnosis of bipolar disorder, schizophrenia/schizoaffective disorder or other psychotic disorder
- Women who are pregnant or nursing
- Terminal medical illness
- Those currently seeing or planning to see a psychiatrist
- Those with suicidal ideation nearly every day
Key Trial Info
Start Date :
March 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2009
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT00459329
Start Date
March 1 2007
End Date
March 1 2009
Last Update
June 4 2008
Active Locations (1)
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1
Regional Epilepsy Center, Harborview Medical Center
Seattle, Washington, United States, 98104