Status:
COMPLETED
Expression of NIS Protein and mRNA in Thyroid Tumors
Lead Sponsor:
University of Sao Paulo
Collaborating Sponsors:
Fundação de Amparo à Pesquisa do Estado de São Paulo
Conditions:
Tumors
Eligibility:
All Genders
18-80 years
Brief Summary
The uptake of iodide by thyroid cells requires the expression of sodium iodide symporter (NIS). Thyroid benign and malignant tumors have low iodide uptake activity. Previous studies of NIS expression ...
Detailed Description
The aim of this study was to quantify NIS transcript levels by real time PCR and to determine the presence and cellular localization of NIS protein by immunohistochemistry, in benign and malignant thy...
Eligibility Criteria
Inclusion
- PAtients with thyroid tumors undergoing surgery for total or partial thyroidectomy
Exclusion
- Pregnancy
Key Trial Info
Start Date :
April 1 2002
Trial Type :
OBSERVATIONAL
End Date :
October 1 2006
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00459498
Start Date
April 1 2002
End Date
October 1 2006
Last Update
April 12 2007
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