Status:
COMPLETED
Sleep Apnea and Refractory Hypertension: Prevalence and Effect of CPAP Treatment
Lead Sponsor:
Fundacio Catalana de Pneumologia
Conditions:
Hypertension
Sleep Apnea
Eligibility:
All Genders
18-75 years
Phase:
PHASE2
Brief Summary
A small number of uncontrolled studies have shown a high prevalence of sleep apnea in patients with refractory hypertension and that CPAP treatment achieves a significant reduction of blood pressure i...
Detailed Description
We assess the prevalence of an apnea hypopnea index (AHI) \> 5 in patients with refractory hypertension referred from a hypertension clinic. Patients with an AHI \>15 are randomized to either continui...
Eligibility Criteria
Inclusion
- Patients referred from a tertiary hospital hypertension clinic with a diagnosis of refractory hypertension on the basis of office blood pressure higher then 160/90 mmHg despite the recommended doses of at least 3 drugs, including a diuretic.
Exclusion
- Causes of secondary hypertension, history of alcohol abuse , renal insufficiency, severe chronically illness.
Key Trial Info
Start Date :
January 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2008
Estimated Enrollment :
130 Patients enrolled
Trial Details
Trial ID
NCT00459914
Start Date
January 1 2005
End Date
December 1 2008
Last Update
January 29 2009
Active Locations (1)
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1
Servei de Pneumologia, Hosital general Universitari Vall d'Hebron
Barcelona, Barcelona, Spain, 08035