Status:

COMPLETED

A Comparative Study of Aleglitazar and Actos in Patients With Type 2 Diabetes Mellitus and New York Heart Association (NYHA) Class II Heart Failure.

Lead Sponsor:

Hoffmann-La Roche

Conditions:

Diabetes Mellitus Type 2

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

This 2 arm study will compare the safety, tolerability and efficacy of aleglitazar and Actos in patients with type 2 diabetes and symptomatic NYHA class II heart failure. Eligible patients will be ran...

Eligibility Criteria

Inclusion

  • adult patients, \>=18 years of age;
  • type 2 diabetes for \>=1 month;
  • drug naive, or receiving stable doses of \<=2 oral antihyperglycemic medications;
  • HbA1c 6.5-10.0% at screening;
  • symptomatic, stable NYHA class 2 heart failure at screening.

Exclusion

  • type 1 diabetes;
  • current or previous treatment with insulin;
  • uncontrolled hypertension;
  • NYHA class 1, 3 or 4 at screening.

Key Trial Info

Start Date :

May 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2007

Estimated Enrollment :

14 Patients enrolled

Trial Details

Trial ID

NCT00461058

Start Date

May 1 2007

End Date

December 1 2007

Last Update

August 5 2016

Active Locations (45)

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Page 1 of 12 (45 locations)

1

Jonesboro, Arkansas, United States, 72401

2

Carmichael, California, United States, 95608

3

Loma Linda, California, United States, 92354

4

Long Beach, California, United States, 90822