Status:
COMPLETED
Effect of Heredity and Environment on Asthma Development and Severity in Puerto Rican Children
Lead Sponsor:
University of Pittsburgh
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Asthma
Hypersensitivity
Eligibility:
All Genders
6-14 years
Brief Summary
Asthma is a major public health problem among Puerto Ricans. Little is known, however, about the effect of heredity and environment on the development and severity of asthma in this population. This s...
Detailed Description
Asthma is a chronic disease that causes constriction of the airways. People with asthma may experience wheezing, coughing, chest tightness, and trouble breathing. Although asthma is a major public hea...
Eligibility Criteria
Inclusion
- For participants with asthma:
- Diagnosis of asthma
- History of wheezing within 12 months prior to study entry
- Has four grandparents that were born in Puerto Rico
- For participants without asthma:
- No diagnosis of asthma
- No history of wheezing within 12 months prior to study entry
- Has four grandparents that were born in Puerto Rico
Exclusion
- Significant pulmonary disease other than asthma
- Hospitalization in the neonatal intensive care unit and requiring ventilatory support
- History of cigarette smoking for more than 5 pack-years (\[number of packs smoked per day\] x \[number of years of smoking\])
Key Trial Info
Start Date :
August 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2010
Estimated Enrollment :
1127 Patients enrolled
Trial Details
Trial ID
NCT00461227
Start Date
August 1 2006
End Date
June 1 2010
Last Update
December 19 2012
Active Locations (1)
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1
University of Puerto Rico
San Juan, Puerto Rico