Status:

TERMINATED

Chromosome Abnormalities in Chronic Myeloid Leukemia (CML) on Imatinib. GIST Patients on Imatinib

Lead Sponsor:

University Health Network, Toronto

Collaborating Sponsors:

Princess Margaret Hospital, Canada

Mount Sinai Hospital, Canada

Conditions:

Chronic Myeloid Leukemia

Gastrointestinal Stromal Cell Tumors

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

In order to distinguish between clonal instability driven by imatinib in CML and actual changes with secondary clones induced by imatinib we would like to investigate the karyotype of non-CML patients...

Detailed Description

Chronic myeloid leukemia (CML) is a myeloproliferative disorder characterized by the presence of the Philadelphia (Ph) chromosome - a t(9:22) translocation that results in the production of a BCR/ABL ...

Eligibility Criteria

Inclusion

  • GIST patient on Imatinib for more than 12 months

Exclusion

  • nil

Key Trial Info

Start Date :

February 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2008

Estimated Enrollment :

68 Patients enrolled

Trial Details

Trial ID

NCT00461929

Start Date

February 1 2005

End Date

December 1 2008

Last Update

February 13 2009

Active Locations (2)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (2 locations)

1

Mount Sinai Hospital

Toronto, Ontario, Canada, M5G 2M9

2

Princess Margaret Hospital

Toronto, Ontario, Canada, M5G 2M9