Status:

COMPLETED

Efficacy and Safety of Green Tea Polyphenol in De Novo Parkinson's Disease Patients

Lead Sponsor:

Xuanwu Hospital, Beijing

Collaborating Sponsors:

Ministry of Health, China

Michael J. Fox Foundation for Parkinson's Research

Conditions:

Parkinson's Disease

Eligibility:

All Genders

30+ years

Phase:

PHASE2

Brief Summary

The purpose of this study is to determine whether Green Tea Polyphenol, an extraction from Green Tea is effective and safe in the treatment of De Novo Parkinson's disease Patients without taking any a...

Detailed Description

The primary outcome measurement is UPDRS using a delay start design. Total 480 de novo PD patients divided into three dosage groups of green tea polyphenol and one placebo control group. Patients will...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • Willing and able to give informed consent
  • Age 30 years or older at time of diagnosis of Parkinson's disease
  • Diagnosed as having typical PD
  • Parkinson's disease duration of no more than 5 years
  • No current dopaminergic or other forms of anti-parkinsonism therapy
  • Hoehn and Yahr stage \< 3

Exclusion

    Key Trial Info

    Start Date :

    April 1 2006

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    March 1 2009

    Estimated Enrollment :

    480 Patients enrolled

    Trial Details

    Trial ID

    NCT00461942

    Start Date

    April 1 2006

    End Date

    March 1 2009

    Last Update

    August 16 2011

    Active Locations (1)

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    Page 1 of 1 (1 locations)

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    Beijing Institute of Geriatrics, Xuanwu Hospital

    Beijing, China, 100053