Status:
COMPLETED
Evaluation of Etomidate on Adrenal Function in Trauma Patients
Lead Sponsor:
University of Tennessee
Conditions:
Adrenal Insufficiency
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Trauma patients are at increased risk for adrenal function insufficiency. A commonly used agent for rapid sequence intubation (RSI) is known to decrease adrenal function. We want to determine the inci...
Detailed Description
The study will have two arms. Patients on one arm will be assigned to receive etomidate (0.3 mg/kg) and succinylcholine (1mg/kg) for RSI. Patients on the other arm will receive standard therapy at thi...
Eligibility Criteria
Inclusion
- Trauma mechanism of injury
- Patient requires rapid sequence induction for ventilatory support
Exclusion
- \<18 years old
- Prisoners
- Pregnant women
- Patients with a history of adrenal insufficiency
- Patients with adrenal trauma documented by CT scan
- Patients receiving corticosteroids in the previous year
Key Trial Info
Start Date :
February 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2006
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00462644
Start Date
February 1 2006
End Date
September 1 2006
Last Update
February 23 2010
Active Locations (1)
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1
Erlanger Medical Center
Chattanooga, Tennessee, United States, 37403