Status:
UNKNOWN
Functional MRI of Cognitive Control in Autism
Lead Sponsor:
UMC Utrecht
Conditions:
Autism
Eligibility:
All Genders
6-12 years
Brief Summary
This study aims to investigate the role of fronto-striatal circuits and cognitive control in the perseverative and inflexible behavior that is a defining feature of autism. We hypothesize that deficit...
Eligibility Criteria
Inclusion
- Aged 6 - 12 years at inclusion
- Inclusion criteria for subjects with autism
- DSM-IV (APA, 1994) diagnosis of autism, according to ADI-R interview
- Inclusion criteria for controls
- No DSM-IV (APA, 1994) diagnosis, according to DISC interview
- No scores in the clinical range on the Child Behavior Checklist (CBCL) and Teacher Rating Form (TRF)
- IQ \> 70
Exclusion
- Major illness of the cardiovascular, the endocrine, the pulmonal or the gastrointestinal system
- Presence of metal objects in or around the body (pacemaker, dental braces)
- History of or present neurological disorder
Key Trial Info
Start Date :
December 1 2007
Trial Type :
OBSERVATIONAL
End Date :
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT00463164
Start Date
December 1 2007
Last Update
April 20 2007
Active Locations (1)
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1
Dept. of Child and Adolescent Psychiatry, UMC Utrecht
Utrecht, Netherlands, 3584CX