Status:

UNKNOWN

The Pharmacological Basis for the Increase in Visual Time Constants Induced by Single Oral Doses of Sildenafil

Lead Sponsor:

University of Cambridge

Conditions:

Erectile Dysfunction

Eligibility:

MALE

18-55 years

Phase:

NA

Brief Summary

Sildenafil and similar drugs have been used for several years to treat erectile dysfunction. It has been noticed that in some people, sildenafil causes a subtle increase in the length of time that vis...

Eligibility Criteria

Inclusion

  • Healthy
  • Male
  • 18-55 years

Exclusion

  • Significant medical or psychiatric illness
  • Cardiac disease
  • Hyper or hypotension
  • Renal disease
  • Liver disease
  • Stroke
  • Sickle cell anaemia
  • Multiple myeloma
  • Leukaemia
  • Bleeding disorders
  • Peyronie's disease
  • Priapism
  • Subjects receiving prescribed medications
  • Subjects with known visual abnormalities other than refractive errors, including retinitis pigmentosa, optic neuropathy

Key Trial Info

Start Date :

August 1 2006

Trial Type :

INTERVENTIONAL

End Date :

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT00463957

Start Date

August 1 2006

Last Update

January 12 2010

Active Locations (1)

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1

University of Cambridge

Cambridge, United Kingdom