Status:
UNKNOWN
A Controlled Study to Assess the Effectiveness of Aerobic Exercise as an Augmentation Therapy for Inpatients With Major Depressive Disorder
Lead Sponsor:
Hadassah Medical Organization
Conditions:
Major Depressive Disorder
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
We will evaluate the effect of a short-term aerobic exercise program as an adjuvant treatment in patients with depression undergoing standard clinical antidepressant medication therapy as compared to ...
Detailed Description
The patients will be randomly assigned to 3 weeks of augmentation therapy (in addition to the antidepressant medication, which will be continued) with either: 1) aerobic exercise or 2) stretching exer...
Eligibility Criteria
Inclusion
- Diagnosis of Major Depressive Episode (MDE) in the context of MDD according to DSM-IV criteria, without psychotic features.
- Hamilton Depression Scale (21 items, HAM-D) total\>14 with item 1 (depressed mood) \>2.
- Physical capability to perform aerobic exercise or stretching exercise.
- Competent and willing to give written informed consent
Exclusion
- Current, significant physical illness that will preclude exercise training.
- Any physical impairment that can interfere with exercise training.
- Current psychotic features.
- Treatment with electroconvulsive therapy.
Key Trial Info
Start Date :
May 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2009
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00464048
Start Date
May 1 2007
End Date
May 1 2009
Last Update
April 20 2007
Active Locations (1)
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1
Hadassah Medical Organization
Jerusalem, Israel