Status:

COMPLETED

Comparison of Efficacy and Safety of Rimonabant 5mg/Day or 20mg/Day Versus Placebo in Smoking Cessation

Lead Sponsor:

Sanofi

Conditions:

Smoking Cessation

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The primary objective is to assess the efficacy of 2 fixed doses of rimonabant versus placebo on abstinence from tobacco use in cigarette smokers. The secondary objective is to evaluate the effects o...

Eligibility Criteria

Inclusion

  • Smokers smoking at least 10 cigarettes/day as a mean within the 2 months preceding the screening visit
  • Motivated to quit with a score greater than or equal to 6 on the ten-point Motivation Scale

Exclusion

  • Non tobacco cigarettes consumption
  • Chronic use of marijuana
  • Pregnancy, breastfeeding
  • Any clinically significant disease that might interfere with the efficacy or safety evaluation of the study drug
  • Concomitant use of drugs as an aid to smoking cessation or that might induce weight change

Key Trial Info

Start Date :

November 1 2002

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2003

Estimated Enrollment :

789 Patients enrolled

Trial Details

Trial ID

NCT00464165

Start Date

November 1 2002

End Date

October 1 2003

Last Update

December 10 2010

Active Locations (7)

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Page 1 of 2 (7 locations)

1

Sanofi-Aventis Administrative Office

Diegem, Belgium

2

Sanofi-Aventis Administrative Office

Hørsholm, Denmark

3

Sanofi-Aventis Administrative Office

Paris, France

4

Sanofi-Aventis Administrative Office

Barcelona, Spain