Status:
UNKNOWN
A Validation/Interventional Study on Stress Index in Predicting Mechanical Stress in ARDS Patients
Lead Sponsor:
University of Turin, Italy
Conditions:
Respiratory Distress Syndrome, Adult
Eligibility:
All Genders
18-85 years
Phase:
PHASE3
Brief Summary
30% of ARDS patients ventilated according to NIH protocol presents CT scan evidence of hyperinflation. Functional analysis of pressure-time curve (Stress Index=SI) has been shown to identify this cond...
Detailed Description
The study presents two parts : a preliminary validation study and a clinical study.
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- Diagnosis of ARDS based on American-European Consensus Conference criteria
Exclusion
- \>3 days since ARDS criteria were met and mechanical ventilation was started
- History of ventricular fibrillation or tachyarrhythmia, unstable angina or myocardial infarction within preceding month
- Pre-existing chronic obstructive pulmonary disease
- Major chest wall abnormalities
- Chest tube with persistent air leak
- Abdominal distension
- Body mass index \>30
- Pregnancy
- Known intracranial abnormality
- Enrollment in another interventional study
Key Trial Info
Start Date :
October 1 2002
Trial Type :
INTERVENTIONAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00465374
Start Date
October 1 2002
Last Update
April 25 2007
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Turin, Department of Anesthesia and Intensive Care Medicine
Turin, Italy