Status:
COMPLETED
Doppler and Biological Second Trimester Placental Insufficiency Screening
Lead Sponsor:
University Hospital, Tours
Conditions:
Pre-Eclampsia
Fetal Growth Retardation
Eligibility:
FEMALE
18-45 years
Brief Summary
To assess the role of uterine artery and maternal serum leptin and lipids and their combination in screening for pre-eclampsia and small-for-gestational-age (SGA) fetuses at 20-24 weeks of gestation
Detailed Description
Pre-eclampsia (PE) and intrauterine growth restriction (IUGR) are known as major factors in perinatal morbidity and mortality. Routine antenatal care is focused on the detection of women at increased ...
Eligibility Criteria
Inclusion
- Chronic hypertension under medication
- Diabetes
- Thrombophilia
- Previous history of pre-eclampsia
- Previous history of unexplained stillbirth
- Previous history of placental abruption
- Previous history of SGA (\< 10th centile)
- History of pre-eclampsia or chronic hypertension before 45 years in the mother or a sister
- Obesity (BMI\>30)
- Nulliparous after 40 years
- Assisted conception with donor
Exclusion
- Multiple pregnancy
- Complicated pregnancy with a high probability of required fetal extraction before term
- Pregnancy requiring termination
- Unability to understand the study
Key Trial Info
Start Date :
May 1 2003
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2007
Estimated Enrollment :
235 Patients enrolled
Trial Details
Trial ID
NCT00465634
Start Date
May 1 2003
End Date
June 1 2007
Last Update
August 9 2013
Active Locations (1)
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1
Olympe de Gouges Women Health Centre, Bretonneau University Hospital
Tours, France, 37044