Status:

TERMINATED

The Effect of Rituximab on the Humoral Response to Influenza Vaccine

Lead Sponsor:

Tel-Aviv Sourasky Medical Center

Conditions:

Rheumatoid Arthritis

Eligibility:

All Genders

18-85 years

Phase:

NA

Brief Summary

Rituximab is a genetically engineered chimeric anti-CD20 monoclonal antibody that selectively targets CD20+ B cells and induces a transient depletion of the CD20+ mature B cell subpopulation.The objec...

Detailed Description

The study population comprised RA patients treated with conventional disease modifying drugs with or without rituximab. Split-virion inactivated vaccine containing 15 mcg hemagglutinin/dose of B/Shang...

Eligibility Criteria

Inclusion

  • Patients with Rheumatoid Arthritis
  • Age-18-85
  • Treatment with Rituximab and other Disease modifying drugs

Exclusion

  • Treatment with anti TNF alpha
  • Allergy to eggs

Key Trial Info

Start Date :

September 1 2005

Trial Type :

INTERVENTIONAL

End Date :

February 1 2006

Estimated Enrollment :

64 Patients enrolled

Trial Details

Trial ID

NCT00466037

Start Date

September 1 2005

End Date

February 1 2006

Last Update

April 27 2007

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The Effect of Rituximab on the Humoral Response to Influenza Vaccine | DecenTrialz