Status:

COMPLETED

Breast Reconstruction and Augmentation With Brava Enhanced Autologous Fat Micro Grafting

Lead Sponsor:

Brava

Conditions:

Mammaplasty

Mastectomy

Eligibility:

FEMALE

18-80 years

Phase:

NA

Brief Summary

The primary objectives of this study is to determine whether use of a negative pressure external soft-tissue expansion system pre-operatively and post-operatively improves and secures graft survival i...

Detailed Description

Procedure: Urine pregnancy test will be performed before each designated procedure in the study. Patients will be questioned about underlying renal disease and excluded if existent. Pre-operative/ba...

Eligibility Criteria

Inclusion

  • Female volunteers between the ages of 18 and 80 years of age and weighing between 100- 275 lbs may be enrolled in the study. Ages 16 to 18 with developmental deformities may be enrolled with parental consent.
  • Post implant removal with subcutaneous defect
  • Post lumpectomy patients with or without radiation therapy with asymmetrical defect
  • Post mastectomy with or without radiation therapy
  • Post flap reconstruction with asymmetry or contour defect
  • Primary breast augmentation
  • Primary Post-mastectomy breast reconstruction
  • Breast asymmetry
  • Other congenital malformation of the breast such as constricted breasts, tubular breast, tuberous breasts, pectus associated deformities and Poland's Syndrome

Exclusion

  • The following volunteers must be excluded from the study:
  • A volunteer who has a positive pregnancy test
  • A volunteer who has a pacemaker or aneurysm clips
  • A volunteer who has had a cardiac stent placed within the last two months
  • A volunteer who is claustrophobic
  • A volunteer with a known, current substance abuse
  • A volunteer with a history of silicone allergy
  • A volunteer with a history of Gadolinium allergy (if MRI performed)
  • A volunteer with a history of Lidocaine allergy
  • A volunteer with a bleeding diathesis
  • Untreated breast cancer
  • A volunteer who smokes cigarettes or who has a history of smoking within the past three (3) months.
  • Medical Conditions including Sever Hypertension, Renal disease, steroid dependant asthma, immuno-suppressed disease, Systemic Lupus, uncontrolled diabetes

Key Trial Info

Start Date :

January 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2015

Estimated Enrollment :

589 Patients enrolled

Trial Details

Trial ID

NCT00466765

Start Date

January 1 2010

End Date

April 1 2015

Last Update

May 5 2015

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Roger K Khouri, MD

Miami, Florida, United States, 33134

2

Miami Breast Center, Medical Office of Roger Khouri MD

Miami, Florida, United States, 33149