Status:
COMPLETED
Optimal Dietary Fat Pattern to Prevent Cardiovascular Disease Among Type 2 Diabetes
Lead Sponsor:
Sun Yat-sen University
Conditions:
Type 2 Diabetes Mellitus
Eligibility:
All Genders
Phase:
PHASE1
PHASE2
Brief Summary
Cardiovascular complications are the leading cause of death among type 2 diabetic patients. Postprandial triglyceride-rich lipoproteins (ppTRLs) are atherogenic. Dietary fatty acid quality, that is, d...
Detailed Description
Atherosclerosis is the leading cause of death and disability among patients with type 2 diabetes mellitus. These patients characteristically have hypertriglyceridemia, high VLDL and low HDL-cholestero...
Eligibility Criteria
Inclusion
- Type 2 diabetes;
- Types and doses of antidiabetic agents had been unchanged for four weeks before the postprandial study;
- Nonsmokers;
- No prior cardiovascular disease, hepatic and renal diseases, or other diseases influencing fat absorption;
- No previous history of gastro-enteral surgery;
- Dietary fat provided energy less than 35% in last two weeks;
- No use of medications or vitamins known to affect plasma lipids;
- Ability to hold hypoglycemic drugs on the day of the study until postprandial tests are completed;
- Ability to provide verbal informed consent to participate.
Exclusion
- Females with menstrual cycles
Key Trial Info
Start Date :
January 1 1998
Trial Type :
INTERVENTIONAL
End Date :
May 1 1998
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00467168
Start Date
January 1 1998
End Date
May 1 1998
Last Update
April 27 2007
Active Locations (2)
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1
Department of Clinical Nutrition, School of Public Health, Sun Yat-sen University
Guangzhou, Guangdong, China, 510080
2
Department of Endocrinology, The First Hospital, Sun Yat-sen University
Guangzhou, Guangdong, China, 510080