Status:

COMPLETED

Investigating Efficacy and Safety of Two Degarelix Three-Month Dosing Regimens in Patients With Prostate Cancer Requiring Androgen Ablation Therapy

Lead Sponsor:

Ferring Pharmaceuticals

Conditions:

Prostate Cancer

Eligibility:

MALE

18+ years

Phase:

PHASE2

Brief Summary

The study will have two treatment groups, evaluating two Degarelix doses. First dose is the initial dose followed by a maintenance dose given every three months. The initial dose given to suppress the...

Detailed Description

An Open-Label, Multi-Centre, Randomized Parallel-Group Dose-Finding Study, Investigating Efficacy and Safety of Two Degarelix Three-Month Dosing Regimens in Patients with Prostrate Cancer Requiring An...

Eligibility Criteria

Inclusion

  • Inclusion / Exclusion Criteria:
  • Patients, aged 18 years or older, with histologically proven prostate cancer of all stages in whom endocrine treatment is indicated.
  • Screening testosterone level above the lower limit of normal range, globally defined as \>2.2 ng/mL.
  • Eastern Cooperative Oncology Group (ECOG) score of ≤2.
  • Screening prostate-specific antigen (PSA) level ≥ ng/mL.

Exclusion

    Key Trial Info

    Start Date :

    May 1 2007

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    August 1 2008

    Estimated Enrollment :

    133 Patients enrolled

    Trial Details

    Trial ID

    NCT00468286

    Start Date

    May 1 2007

    End Date

    August 1 2008

    Last Update

    March 23 2011

    Active Locations (29)

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    Page 1 of 8 (29 locations)

    1

    Urology Centers of Alabama

    Homewood, Alabama, United States, 35209

    2

    South Orange County Medical Research Center

    Laguna Woods, California, United States, 92653

    3

    South Florida Medical Research

    Aventura, Florida, United States, 33180

    4

    Florida Foundation for Healthcare Research

    Ocala, Florida, United States, 34474