Status:

COMPLETED

Phase 3/Safety & Efficacy of Esomeprazole in Infants

Lead Sponsor:

AstraZeneca

Conditions:

Gastroesophageal Reflux Disease (GERD)

Eligibility:

All Genders

1-11 years

Phase:

PHASE3

Brief Summary

The purpose of this study is to look at the improvement of a once a day dose of esomeprazole for reducing the signs and symptoms of infants with gastroesophageal reflux disease (GERD). This research s...

Eligibility Criteria

Inclusion

  • patients' parents must sign the informed consent prior to the beginning of any study-related procedures (according to local regulations)
  • patients must have symptoms at study entry and have a clinical diagnosis of suspected GERD, symptomatic GERD, or GERD proven by a test called an endoscopy, a test using a long tube inserted in the body for diagnostic exams

Exclusion

  • patients who have used a PPI (proton pump inhibitors; used to reduce the amount of acid in the stomach) within 7 days before enrollment in the open label treatment phase (Day 0)
  • patients with a history of acute life-threatening event

Key Trial Info

Start Date :

April 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2008

Estimated Enrollment :

98 Patients enrolled

Trial Details

Trial ID

NCT00468559

Start Date

April 1 2007

End Date

June 1 2008

Last Update

June 2 2014

Active Locations (25)

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Page 1 of 7 (25 locations)

1

Research Site

Phoenix, Arizona, United States

2

Research Site

Atlanta, Georgia, United States

3

Research Site

Park Ridge, Illinois, United States

4

Research Site

Louisville, Kentucky, United States

Phase 3/Safety & Efficacy of Esomeprazole in Infants | DecenTrialz