Status:
COMPLETED
Tetracycline (Doxycycline) and Post Myocardial Infarction Remodeling
Lead Sponsor:
Careggi Hospital
Conditions:
Myocardial Infarction
Left Ventricular Remodeling
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
The aim of the study is to assess the efficacy of an antibiotic treatment with tetracycline (doxycycline) in the early stage of large reperfused acute myocardial infarction (AMI), in preventing left v...
Detailed Description
A myocardial interstitial matrix, that provides structural support and integrity to the myocardium, is a key element to determine post infarction left ventricular remodeling (LVR). The metalloprotein...
Eligibility Criteria
Inclusion
- Acute myocardial infarction
- Left ventricular ejection fraction less than 40%
Exclusion
- No written consensus
- Allergy to tetracycline
- Mechanical complication of AMI
- Previous myocardial infarction
- Valvular and/or myocardiopathy known or suspected
- Renal failure (creatinine above 2 mg/dL)
- Connective tissue disease
- Pregnancy
Key Trial Info
Start Date :
May 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2011
Estimated Enrollment :
110 Patients enrolled
Trial Details
Trial ID
NCT00469261
Start Date
May 1 2007
End Date
August 1 2011
Last Update
September 25 2012
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.