Status:
COMPLETED
Flossing With Chlorhexidine
Lead Sponsor:
University of British Columbia
Collaborating Sponsors:
Canadian Foundation for Dental Hygiene Research and Education
British Columbia Dental Hygienists' Association (BCDHA)
Conditions:
Gingivitis
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
To determine if flossing with a dental floss presoaked in chlorhexidine, an anti-microbial mouth wash, would improve the clinical signs of gingivitis, an inflammation of the gums characterized by red,...
Detailed Description
Purpose of study: To determine if dental floss presoaked in 0.12% chlorhexidine is more effective at reducing the signs of gingivitis, such as bleeding, than a dental floss in placebo solution of 0.1%...
Eligibility Criteria
Inclusion
- To be considered for inclusion into the study, subjects must fulfill the following conditions:
- 18 years and older
- Have gingivitis (i.e., have pocket depths of 4 mm or less), but not periodontitis
- Willing to floss every day and have the necessary dexterity to floss
- Have a minimum of 20 natural teeth, including 4 molars
- Have at least 10 bleeding sites
- Be a non-smoker
Exclusion
- Subjects will be excluded from the study, if they have any of the following conditions:
- Pregnant or plan to be pregnant within the next 3 months
- Allergic to chlorhexidine or quinine sulphate
- Require pre-medication with antibiotics for dental treatment
- Currently taking antibiotics
- Currently taking Dilantin, Cyclosporin A, Nifedipine or other calcium channel blockers, aspirin or anti-coagulants
- Currently using chlorhexidine or whitening products
- Have active carious lesions
- Have orthodontic braces
- Have more than 2 crowns or bridges
- Have more than 2 implants
- Have full or partial dentures
- Have periodontitis, i.e., pocket depths of 5 mm or more in more than 2 sites in the mouth
Key Trial Info
Start Date :
April 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2006
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT00471783
Start Date
April 1 2006
End Date
December 1 2006
Last Update
August 15 2008
Active Locations (1)
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1
Dr. Ian Low
2031 West 41st Avenue, Vancouver, British Columbia, Canada