Status:

UNKNOWN

A Comparison of Factors of Symptoms Generation and Evaluation of Role of Biofeedback in Patients With Different Types of Functional Esophageal Disorders (Functional Heartburn and Functional Chest Pain)

Lead Sponsor:

Assaf-Harofeh Medical Center

Conditions:

Chest Pain

Heartburn

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

There is supposed that patients with functional esophageal disorders such as functional heartburns and functional chest pain have common underlying mechanisms of symptom generation. These include esop...

Eligibility Criteria

Inclusion

  • Men and women ages 18-75.
  • Willing to participate and sign an inform consent.
  • Having heartburns, acid regurgitations and/or chest pain at least twice a week for at least 3 months.
  • Ability to stop anti-acid and anti-pain medications for at least two weeks.

Exclusion

  • History of upper gastrointestinal surgery.
  • Concomitant diseases that may affect esophageal perception (diabetes mellitus, neuropathy).
  • Concomitant medications that may affect esophageal perception (anti-inflammatory, anti-depressants drugs).
  • Pregnancy.
  • Severe conditions such as cardiac failure, renal failure and other that may be contraindication for upper endoscopy.
  • Erosive esophagitis on upper endoscopy or pathological result of ambulatory 24-hour pH monitoring.

Key Trial Info

Start Date :

Trial Type :

INTERVENTIONAL

End Date :

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00471796

Last Update

May 10 2007

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