Status:

COMPLETED

ProLOVE - Prospective Randomized Study of Midline Incisional Hernia Treatment

Lead Sponsor:

Skane University Hospital

Collaborating Sponsors:

Region Skåne FoUU

Lund University

Conditions:

HERNIA, VENTRAL

Eligibility:

All Genders

18+ years

Brief Summary

This purpose of this study is to compare the recovery after an operation of an incisional hernia within the limits of the rectus muscles of the abdominal wall. The use of a mesh in the repair of a pos...

Detailed Description

Incisional ventral hernia after abdominal surgery is a fairly common condition. In recent years the use of a prosthesis in the repair procedure has proved very effective in preventing a new hernia. A ...

Eligibility Criteria

Inclusion

  • Age over 18 years
  • Postoperative hernias in the region of the recti abdomini muscles with a defect of less than 10 cm transversal width
  • No contraindications to laparoscopic procedure
  • The patient should be able to adequate ventilation/respiration after reduction of hernia contents
  • Indications for elective surgery

Exclusion

  • Pregnant women
  • Prior operation of abdominal hernia with mesh placement in the compartment of the rectus abdominus muscle (i.e. prior onlay mesh is acceptable)
  • Need of an interpreter
  • Current drug abuse, mental disorder or other condition which makes the patient incapable of postoperative follow up
  • Body Mass index (BMI) \>40
  • Other planned concurrent operation
  • Current oral steroid treatment, or other immune system modulating treatment
  • Incarcerated incisional hernias
  • Parastomal hernias
  • Prior history of open abdomen
  • Enterocutaneous fistula or cutaneous infection
  • Hepatic cirrhosis or ascites
  • Generalized malignancy
  • History of radiation treatment in the abdomen.
  • ASA \>III

Key Trial Info

Start Date :

November 1 2005

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 1 2010

Estimated Enrollment :

157 Patients enrolled

Trial Details

Trial ID

NCT00472537

Start Date

November 1 2005

End Date

November 1 2010

Last Update

April 24 2013

Active Locations (7)

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Page 1 of 2 (7 locations)

1

Malmö University Hospital, Department of Surgery

Malmo, Malmö, Sweden, 20502

2

Arvika Hospital, Department of Surgery

Arvika, Sweden, SE-671 80

3

Helsingborg Hospital, Department of Surgery

Helsingborg, Sweden, 251 87

4

Lund University Hospital, Department of Surgery

Lund, Sweden, SE-222 41