Status:
COMPLETED
Prevention of Contrast Induced Nephropathy With Sodium Bicarbonate
Lead Sponsor:
Universidad de Antioquia
Conditions:
Acute Kidney Failure
Eligibility:
All Genders
18+ years
Phase:
PHASE2
PHASE3
Brief Summary
Deterioration of kidney renal function occurs in a minority of people due to contrast-required procedures. The purpose of this study is to compare two different interventions to reduce the risk of kid...
Detailed Description
We will perform a randomized clinical trial following a modification of a previously published protocol (Merten et al.JAMA 2004;291(19):2328-34). Patients will be randomly assigned to one of two group...
Eligibility Criteria
Inclusion
- 18+ years of age
- Inpatient at Hospital Universitario San Vicente de Paúl scheduled to undergo diagnostic CT scan using contrast or angiography and either
- Serum creatinine 1.2 mg/dl or more, or
- Type 2 Diabetes Mellitus
Exclusion
- Current clinical diagnosis of exacerbated congestive heart failure
- Exposure to contrast 30 days prior to study
- Allergy to contrast dye
- Chronic renal disease with dialysis therapy
- Acute renal failure with dialytic urgency
- Urgency procedure needed
- Systolic blood pressure \< 90 or vasopressor support
- No authorization by patient or physician in charge
- Serum potassium \< 3 mEq/L
- Ejection fraction \< 35% by previous echocardiography
- Acute pulmonary edema in previous 48 hours
Key Trial Info
Start Date :
May 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2008
Estimated Enrollment :
212 Patients enrolled
Trial Details
Trial ID
NCT00472563
Start Date
May 1 2007
End Date
February 1 2008
Last Update
May 6 2008
Active Locations (1)
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1
Hospital Universitario San Vicente Paúl
Medellín, Antioquia, Colombia, 57