Status:

COMPLETED

The Effect of Vitamin D Supplementation During Caloric Restriction on Intestinal Calcium Absorption

Lead Sponsor:

Rutgers University

Collaborating Sponsors:

National Institute on Aging (NIA)

Conditions:

Weight Loss

Vitamin D or Placebo

Eligibility:

FEMALE

50-72 years

Phase:

NA

Brief Summary

The purpose of this study is to learn how the amount of vitamin D supplementation influences intestinal fractional calcium absorption (a measure of the amount of calcium absorbed).

Detailed Description

The extent of change in the amount of calcium that is absorbed with an increase in vitamin D supplementation is not known. This information is important for determining appropriate vitamin D requireme...

Eligibility Criteria

Inclusion

  • Postmenopausal women who are more than 2 years since last menses
  • Obese or overweight
  • Must live in the geographic vicinity of Rutgers University

Exclusion

  • Currently on any medication known to influence calcium or bone metabolism, including HRT, or with evidence of diseases known to influence calcium metabolism (i.e. metabolic bone disease, hyperparathyroidism, untreated thyroid disease, significant immune, hepatic, or renal disease, significant cardiac disease \[i.e., heart attack or stroke in the past 6 months., abnormal EKG\], active malignancy or cancer therapy within the past year)
  • History of kidney stones
  • Weight gain or weight loss (5% of body wt) within 3 months prior to recruitment
  • Participation in other investigational studies during the study period
  • Travel for longer than 2 consecutive weeks during the study period
  • Usually have a very high or low intake of calcium (more than 1500 or less than 500 mg per day)

Key Trial Info

Start Date :

March 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2011

Estimated Enrollment :

83 Patients enrolled

Trial Details

Trial ID

NCT00472654

Start Date

March 1 2007

End Date

March 1 2011

Last Update

March 28 2023

Active Locations (1)

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1

Rutgers University

New Brunswick, New Jersey, United States, 08901