Status:

TERMINATED

The Effect of Severe Weight Loss and Protein Intake on Bone

Lead Sponsor:

Rutgers University

Collaborating Sponsors:

National Institute on Aging (NIA)

Conditions:

Weight Loss

Eligibility:

FEMALE

18-70 years

Phase:

NA

Brief Summary

The purpose of this study is to learn whether the amount of dietary protein can influence bone health during the weight loss after weight loss surgery.

Detailed Description

It is unclear whether the amount of protein in the diet during caloric restriction influences bone density. This information is important for determining optimal nutrient requirements during weight lo...

Eligibility Criteria

Inclusion

  • Women ages 18 to 70 who are undergoing gastric bypass surgery
  • Must live in the geographic vicinity of Rutgers University

Exclusion

  • Currently on any medication known to influence calcium or bone metabolism, including HRT, or with evidence of diseases known to influence calcium metabolism (i.e. metabolic bone disease, hyperparathyroidism, untreated thyroid disease, significant immune, hepatic, or renal disease, significant cardiac disease \[i.e., heart attack or stroke in the past 6 months., abnormal EKG\], active malignancy or cancer therapy within the past year)
  • History of kidney stones
  • Weight gain or weight loss (5% of body wt) within 3 months prior to recruitment
  • Participation in other investigational studies during the 12-month study period
  • Usually have a very high or low intake of calcium (more than 1500 or less than 500 mg per day)

Key Trial Info

Start Date :

March 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2016

Estimated Enrollment :

5 Patients enrolled

Trial Details

Trial ID

NCT00472680

Start Date

March 1 2010

End Date

January 1 2016

Last Update

February 1 2022

Active Locations (1)

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Rutgers University

New Brunswick, New Jersey, United States, 08901