Status:

COMPLETED

Contact Lens in Pediatrics (CLIP) in an Asian Population Study

Lead Sponsor:

Singapore National Eye Centre

Conditions:

Myopia

Eligibility:

All Genders

8-11 years

Phase:

NA

Brief Summary

To evaluate the safety, efficacy and physiological performance of daily disposable spherical and toric soft contact lenses in a vision-corrected population of children ages 8-11 years of age. To evalu...

Detailed Description

This is a bilateral, open-label dispensing evaluation of two daily lens types. Eligible subjects will wear the study lenses for 3-months daily wear. 1-Day Acuvue will be worn by spherical subjects and...

Eligibility Criteria

Inclusion

  • Be between 8-11 years of age.
  • Signed Written Informed Consent and/or have the consent of a parent or legal guardian and Investigator to record this on Case Report Form (CRF) in appropriate space.
  • Be a neophyte.
  • Require a visual correction in both eyes.
  • Require a soft contact lens spherical correction between +5.00 and -9.00 DS.
  • Have an astigmatic correction between 0.00 amd 2.00 DC.
  • Be able to wear the lens powers available for this study.
  • Be correctable to a visual acuity of 20/25 or better in each eye.
  • Have normal eyes with no evidence of abnormality or disease. For the purposes of this study a normal eye is defined as one having:
  • (i)No amblyopia. (ii) No evidence of lid abnormality or infection. (eg. entropion, ectropion, chalazia, recurrent styes). (iii) No clinically significant slit lamp (eg. any infiltrates or other slit lamp findings Grade 3 or above: corneal edema, corneal staining, tarsal abnormalities, conjunctival injection, vascularisation, or abnormal opacities).(iv) No other active ocular disease. (eg. glaucoma, history of recurrent corneal erosions, cornea infiltrates, conjunctiva, lids, and intraocular infection or inflammation of an allergic, bacterial, or viral etiology.)

Exclusion

  • Requires concurrent ocular medication.
  • Any systemic illness which would contraindicate lens wear or the medical treatment of which would affect vision or successful lens wear.
  • No clinically significant (Grade 3 or 4) slit lamp findings including corneal edema, corneal vascularization, corneal staining, tarsal abnormalities, bulbar injection, or any other abnormality of the cornea that would contraindicate contact lens wear.
  • Diabetic.
  • Infectious disease (eg.hepatitis, tuberculosis)or an immunosuppressive disease (eg.HIV).
  • PMMA or RGP lens wear in the previous 8 weeks.
  • Has had refractive surgery. Has had eye injury/surgery within 8 weeks immediately prior to enrollment for this study.
  • Abnormal lacrimal secretions.
  • Pre-existing ocular irritation that would preclude contact lens fitting.
  • Keratoconus or other corneal irregularity.
  • Pregnancy, lactating or planning a pregnancy at the time of enrollment only.
  • Participation in any concurrent clinical trial.

Key Trial Info

Start Date :

December 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

November 1 2008

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT00473304

Start Date

December 1 2006

End Date

November 1 2008

Last Update

May 12 2010

Active Locations (1)

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Singapore National Eye Centre

Singapore, Singapore