Status:

COMPLETED

12 Week Study Of PF-00734200 For The Treatment Of Type 2 Diabetes Mellitus In Subjects Treated With Metformin

Lead Sponsor:

Pfizer

Conditions:

Diabetes Mellitus, Type 2

Eligibility:

All Genders

18-70 years

Phase:

PHASE2

Brief Summary

The purpose of this Phase 2a study is to evaluate the efficacy, safety and tolerability, of multiple parallel doses of PF-00734200 following oral administration to adult human subjects with T2DM who c...

Eligibility Criteria

Inclusion

  • Diagnosis of type 2 diabetes
  • Hb1AC \>7%-11% inclusive
  • Male and females 18-70; females must be post-menopausal
  • On a stable dose of metformin hydrochloride

Exclusion

  • Medical history of stroke, unstable angina, heart attack within one year of enrollment, and alcohol dependency or recent drug abuse.
  • Women of childbearing potential, pregnant or nursing
  • Evidence of diabetic complications with significant end-organ damage

Key Trial Info

Start Date :

July 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2008

Estimated Enrollment :

303 Patients enrolled

Trial Details

Trial ID

NCT00473525

Start Date

July 1 2007

End Date

June 1 2008

Last Update

June 24 2010

Active Locations (79)

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Page 1 of 20 (79 locations)

1

Pfizer Investigational Site

Birmingham, Alabama, United States, 35209

2

Pfizer Investigational Site

Gilbert, Arizona, United States, 85296

3

Pfizer Investigational Site

Phoenix, Arizona, United States, 85013

4

Pfizer Investigational Site

Phoenix, Arizona, United States, 85016