Status:

COMPLETED

Structured Exercise Training Program Versus Hypocaloric Hyperproteic Diet in Obese Anovulatory Infertile Patients With PCOS

Lead Sponsor:

University Magna Graecia

Conditions:

Polycystic Ovary Syndrome

Anovulation

Eligibility:

FEMALE

18-35 years

Phase:

PHASE4

Brief Summary

Lifestyle modifications are successfully employed in polycystic ovarian syndrome (PCOS) improving menstrual cycles and fertility. Unfortunately, the compliance over the time is very low. Recently, we ...

Detailed Description

Forty obese anovulatory infertile PCOS patients who wish to conceive will be allocated in two study-groups according to their desire: structured exercise training (SET) group (n. 20) will undergo a SE...

Eligibility Criteria

Inclusion

  • PCOS
  • Anovulatory infertility
  • Obesity (BMI \>30)

Exclusion

  • Age \<18 or \>35 years
  • Neoplastic, metabolic, hepatic, renal, and cardiovascular disorders or other concurrent medical illnesses
  • Hypothyroidism, hyperprolactinemia, Cushing's syndrome, and non-classical congenital adrenal hyperplasia
  • Current or previous (within the last six months) use of oral contraceptives, glucocorticoids, antiandrogens, ovulation induction agents, antidiabetic and anti-obesity drugs or other drugs know to affect sex hormone levels, carbohydrate metabolism, or appetite
  • Organic pelvic diseases, previous pelvic surgery, suspected peritoneal factor infertility, tubal or male factor infertility or sub-fertility

Key Trial Info

Start Date :

January 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2006

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT00473538

Start Date

January 1 2004

End Date

August 1 2006

Last Update

November 14 2007

Active Locations (1)

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1

"Pugliese" Hospital

Catanzaro, Italy, 88100