Efficacy and safety of dopamine versus norepinephrine in the management of septic shock.
Gourang P Patel, Jaime Simon Grahe, Mathew Sperry...
https://pubmed.ncbi.nlm.nih.gov/19851126Completed
Phase 3
Age: 18Years +
All Genders
ID00604019
Dopamine Versus Norepinephrine for the Treatment of Vasopressor Dependent Septic Shock
Led by Rush University Medical Center · Updated on 2023-01-11
252
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
We are performing a prospective, randomized, controlled trial of dopamine versus norepinephrine for septic shock. The trial will enroll patients with suspected or documented site of infection and having 2 out of the three SIRS criteria. Patients will also be receiving standard of care, early-goal directed therapy including but not limited to fluid resuscitation, appropriate and early antibiotics, source control and evaluation for drotrecogin alpha where deemed appropriate, while being supported for septic shock.
CONDITIONS
Brief Title
Dopamine Versus Norepinephrine for the Treatment of Vasopressor Dependent Septic Shock
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Patients are transferred to our medical intensive care unit from the emergency room (ER), general medical floors, and from outside hospitals.
- Patients were eligible if they were greater than 18 years of age
- Presented with a diagnosis of SIRS plus a suspected or documented source of infection.
You will not qualify if you...
- Patients were not eligible if they were found to have hypovolemic and/or hemorrhagic etiologies of their vasodilatory shock or another etiology of their SIRS.
Trial Site Locations
Total: 1 location
1
RUSH University Medical Center
Chicago, Illinois, United States, 60612
Status Unknown
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How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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