Status:
COMPLETED
Prevention of Acute Voiding Difficulty After Radical Proctectomy
Lead Sponsor:
Seoul National University Hospital
Conditions:
Rectal Cancer
Urinary Retention
Eligibility:
All Genders
20-80 years
Phase:
PHASE3
Brief Summary
Various adrenergic blockers are used for acute voiding difficulty after proctectomy. Recently, a selective alpha5-adrenergic blocker, Tamsulosin has been reported to have benefit in reducing urinary s...
Detailed Description
Acute voiding difficulty is caused from damage to pelvic sympathetic nerve after rectal surgery, and usually resolved spontaneously within several months after the surgery. However, acute voiding diff...
Eligibility Criteria
Inclusion
- Patients between 20-80 years old in general good health
- Patient willing to participate in the study
- Patient who understands and accepts to sign the informed consent form
- Patient who received proctectomy for rectal cancer located 15 cm or less of the anal verge
Exclusion
- Documented problem of preoperative urinary dysfunction
- Any post-surgery change in patient condition which requires insertion of urinary catheter after surgery
- Past history of recurrent urinary tract infection or malignancy of urinary system organs
- Past history of surgery for urinary system organs
- Current administration of Finasteride or Dutasteride
- Liver dysfunction (SGOT or SGPT 100 IU/L or more)
- Kidney dysfunction (serum Creatinine 3mg/dl or more)
Key Trial Info
Start Date :
May 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2010
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00606983
Start Date
May 1 2007
End Date
September 1 2010
Last Update
July 20 2011
Active Locations (1)
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1
Department of Surgery, Seoul National University Bundang Hospital
Seongnam, South Korea, 463-707