Status:
COMPLETED
A Study on the Effects of Feeding and Feeding Methods on Breathing Pattern in Very Low Birth Weight Preterm Infants
Lead Sponsor:
Sunnybrook Health Sciences Centre
Collaborating Sponsors:
The Physicians' Services Incorporated Foundation
Conditions:
Infant, Premature
Apnea
Eligibility:
All Genders
1-12 years
Brief Summary
In this study, we want to see how feeding affects breathing in small premature babies. Using a special feeding tube in the stomach, we can measure how the diaphragm (a large breathing muscle) might be...
Detailed Description
Premature babies may have pauses in breathing known as apnea, which may require invasive treatment. The exact cause of apnea is unknown, and may be related to a combination of brain, gut, and lung imm...
Eligibility Criteria
Inclusion
- Preterm infants \>23 weeks gestation
- Birth weight \<1250 grams
- Not requiring full mechanical ventilation
- Tolerating full regular bolus feeding for at least 48 hours
Exclusion
- Congenital and acquired problem of the gastrointestinal tract
- Phrenic nerve injury and/or diaphragm paralysis
- Esophageal perforation/tracheoesophageal fistula
- Congenital/acquired neurological deficit and/or seizures
- Hemodynamic instability
- Congenital heart disease (including symptomatic patent ductus arteriosus)
- Undergoing treatment for sepsis or pneumonia
- Use of muscle relaxants, narcotic analgesics, or gastric motility agents
Key Trial Info
Start Date :
March 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2008
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT00607555
Start Date
March 1 2008
End Date
December 1 2008
Last Update
November 2 2009
Active Locations (1)
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1
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada, M5S1B2