Status:

TERMINATED

Combined MRI and Optical Imaging to Improved Breast Cancer Diagnosis

Lead Sponsor:

University of California, Irvine

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Breast Cancer

Eligibility:

FEMALE

21-90 years

Phase:

NA

Brief Summary

This study investigates whether adding the optical imaging to magnetic resonance imaging can improve the diagnostic specificity of breast cancer.

Detailed Description

This proposal will investigate the performance of a combined optical-MRI imaging system in diagnosis of breast cancer. A diffuse optical tomography (DOT) imaging system will be integrated with a 3.0 T...

Eligibility Criteria

Inclusion

  • A female older than 21 years of age,
  • Have suspicious imaging findings suggesting a possibility of breast cancer, or biopsy-proven breast cancer.

Exclusion

  • Pregnant,
  • Unwilling to give informed consent,
  • Have implanted prosthetic heart valves, pacemaker, neuro-stimulation devices, surgical clips (hemostatic clips) or other metallic implants,
  • Have engaged in occupations or activities which may cause accidental lodging of ferromagnetic materials, or have imbedded metal fragments from military activities,
  • Have received orthodontic work involving ferromagnetic materials,
  • Claustrophobic,
  • Have had allergic response to contrast agents (such as iodine or gadolinium) previously,
  • Have known history of severe renal insufficiency, asthma, allergic conditions, sickle cell anemia, chronic hemolytic anemia, and gastrointestinal disorders.

Key Trial Info

Start Date :

October 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 30 2017

Estimated Enrollment :

2 Patients enrolled

Trial Details

Trial ID

NCT00610467

Start Date

October 1 2006

End Date

October 30 2017

Last Update

April 20 2020

Active Locations (1)

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Center for Functional Onco-Imaging, University of California

Irvine, California, United States, 92697

Combined MRI and Optical Imaging to Improved Breast Cancer Diagnosis | DecenTrialz