Status:
COMPLETED
Tear Film Stability After Instillation of Over-the-Counter (OTC) Artificial Drops
Lead Sponsor:
University of Texas Southwestern Medical Center
Conditions:
Dry Eye Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal of this research is to evaluate and compare the effectiveness of Systane® versus Optive™ on aqueous tear film stability in patients with a diagnosis of Dry Eye Syndrome and to determine the p...
Detailed Description
Twenty (20) patients will be enrolled in this two-period crossover, randomized study design. During the course of the study, each patient will be treated with each test article in the clinic at separa...
Eligibility Criteria
Inclusion
- Individuals aged 18 and up will be included, where any age over 89 will be recorded as 'greater than 89.'
- Individuals with bilateral eye sight eye correctable to 20/80 or better.
- Individuals in good health with or without Meibomian Gland Dystrophy (MGD) but with Aqueous Tear Deficiency (ATD) with minimal to no ocular surface inflammation on slit lamp examination.
Exclusion
- Individuals with only one sighted eye or vision not correctable to 20/80 or better in both eyes.
- Individuals with history of punctal plugs or punctal occlusions.
- Individuals with history of keratorefractive as well as ophthalmic disease such as corneal dystrophies, glaucoma, or systemic disease affecting the eye (such as Herpes Zoster).
- Individuals with history of systemic or ocular auto-immune conditions.
- Individuals with active systemic disease or those taking systemic medication that are known to influence AT production will not be considered for this trial.
- Individuals using topical medication who are unable to discontinue them for at least 24 hours prior to baseline evaluation will be excluded as well.
Key Trial Info
Start Date :
November 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2009
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00610480
Start Date
November 1 2007
End Date
March 1 2009
Last Update
November 19 2020
Active Locations (1)
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1
UTSW Medical Center at Dallas - Aston Ambulatory Care Center
Dallas, Texas, United States, 75390-9057