Status:
COMPLETED
Studying the Effect of Freeze-Dried Table Grape Powder on Blood Estrogen Levels in Postmenopausal Women
Lead Sponsor:
Mayo Clinic
Conditions:
Breast Cancer
Eligibility:
FEMALE
18-120 years
Brief Summary
RATIONALE: Estrogen can cause the growth of breast cancer cells. Studying samples of blood and urine in the laboratory from participants receiving freeze-dried table grape powder may help doctors unde...
Detailed Description
OBJECTIVES: * To measure the change in levels of plasma estrone (E1), estradiol, E1-conjugates, and E1-sulfates in postmenopausal women after 6 weeks of daily ingestion of 94 grams of freeze-dried ta...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Participant in the Mayo Mammography Health Study
- Has consented to provide baseline mammogram for digitization
- PATIENT CHARACTERISTICS:
- ECOG performance status 0-1
- Female
- Postmenopausal (defined as women who have had both ovaries removed or no menstrual period for at least 12 consecutive months)
- Able to give informed consent and complete food records alone or with assistance
- Willing to provide research blood and urine samples
- Must be a non-smoker
- Willing to maintain current weight
- No history of breast ductal carcinoma in situ or any other cancer, except basal cell or squamous cell skin cancer or lobular carcinoma in situ
- No history of allergic or other adverse reaction to grapes
- No history of diabetes or glucose intolerance
- PRIOR CONCURRENT THERAPY:
- No concurrent hormone therapy, including estradiol, estrone, or progestins
Exclusion
Key Trial Info
Start Date :
August 4 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 22 2014
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00611104
Start Date
August 4 2008
End Date
August 22 2014
Last Update
September 19 2024
Active Locations (1)
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1
Mayo Clinic
Rochester, Minnesota, United States, 55905