Status:
COMPLETED
Atorvastatin for Prevention of Postoperative Atrial Fibrillation After Off-Pump Coronary Artery Bypass Grafting Surgery
Lead Sponsor:
Samsung Medical Center
Conditions:
Coronary Artery Bypass
Eligibility:
All Genders
Phase:
NA
Brief Summary
The purpose of this study is to determine whether pretreatment with atorvastatin protects against atrial fibrillation following off-pump coronary artery bypass graft surgery.
Detailed Description
Atrial fibrillation after cardiac surgery is the most common arrhythmic complication that may increase incidence of congestive heart failure, renal insufficiency, and stroke, which increase the length...
Eligibility Criteria
Inclusion
- consecutive patients scheduled for the elective off-pump CABG surgery
Exclusion
- prior statin use
- previous episodes of atrial fibrillation
- impaired renal function with serum creatinine \>2mg/dL
- serum aspartate aminotransferase or alanine aminotransferase concentrations more than 3 times the upper limit of normal
- a malignancy or inflammatory disease
Key Trial Info
Start Date :
May 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2007
Estimated Enrollment :
124 Patients enrolled
Trial Details
Trial ID
NCT00611143
Start Date
May 1 2006
End Date
May 1 2007
Last Update
February 8 2008
Active Locations (1)
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1
Cardiac and Vascular Center; Samsung Medical Center
Seoul, South Korea, 135-710