Status:
COMPLETED
The Use of Antimicrobial Agents in the Inhibition of Mutans Streptococci in Children With Dental Caries
Lead Sponsor:
Universidade Federal do Ceara
Conditions:
Dental Caries
Eligibility:
All Genders
4-8 years
Phase:
NA
Brief Summary
The aim of the present study was to compare salivary MS levels in four different groups of children with caries, that have been submitted to intraoral topical treatment with either 1,23% sodium fluori...
Detailed Description
The present study aimed to compare the effect of sodium fluoride, chlorhexidine and vancomycin on salivary mutans streptococci (MS) levels, on a double-blind, randomized clinical trial. Sixty-nine hea...
Eligibility Criteria
Inclusion
- Generally healthy children
- Children with at least one carious cavitated or non-cavitated lesion
- Must be able to spit
- Must be able to collaborate during clinical intervention
Exclusion
- Children with history of allergies or allergic diseases, e.g. asthma, urticaria, rhinitis, sinusitis, or intra-oral soft tissue lesions
- Children who underwent antibiotic treatment during the course of this clinical trial
- Children with developmental disabilities
- Children with no clinical signs dental caries
Key Trial Info
Start Date :
October 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2006
Estimated Enrollment :
69 Patients enrolled
Trial Details
Trial ID
NCT00612469
Start Date
October 1 2005
End Date
October 1 2006
Last Update
February 11 2008
Active Locations (1)
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1
School of Dentistry, Department of Clinical Dentistry, Federal University of Ceara
Fortaleza, Ceará, Brazil, 60441-750