Status:
COMPLETED
Streptococcal Infection and Respiratory Distress in Newborns
Lead Sponsor:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Conditions:
Group B Streptococci
Respiratory Distress in Newborn
Eligibility:
All Genders
Brief Summary
This study will evaluate whether babies are more at risk of developing breathing problems if their mothers carry group B streptococci (GBS) in vagina/rectum, and whether the breathing problem is due t...
Detailed Description
Phospholipids from the group B streptococcal (GBS) cell wall cause pulmonary hypertension in experimental animals. We hypothesize that newborns colonized with GBS receive bacterial phospholipids leadi...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- All women who are admitted to labor and delivery room at greater than or equal to 32 weeks gestation will be approached for obtaining consent to participate in this study.
- EXCLUSION CRITERIA:
- Newborns with severe or fatal congenital anomaly such as gastroschisis, congenital diaphragmatic hernia, tracheoesophageal fistula, transition of the great arteries, coarctation of aorta, myelomeningocele, and omphalocele will be excluded from the study.
Exclusion
Key Trial Info
Start Date :
February 4 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 19 2015
Estimated Enrollment :
13180 Patients enrolled
Trial Details
Trial ID
NCT00612937
Start Date
February 4 2008
End Date
June 19 2015
Last Update
April 5 2018
Active Locations (2)
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1
Oakland Children's Hospital and Research Center
Oakland, California, United States, 94609
2
Baylor College of Medicine
Houston, Texas, United States, 77030