Status:
COMPLETED
Effect of Topical Morphine (Mouthwash) on Oral Pain Due to Chemo- and/or Radiotherapy Induced Mucositis
Lead Sponsor:
University Hospital, Geneva
Conditions:
Cancer
Mucositis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Introduction: Oral pain due to mucosal lesion is quite frequent in oncology, geriatric as well as palliative care settings. The oncology patient is mainly suffering from radio- and/or chemotherapy in...
Detailed Description
randomised double-blind cross-over study to evaluate the effect of topical oral application of a 0.2% morphine solution in patients suffering from radio- and/or chemotherapy induced oral mucositis. 60...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Hospitalised patients, or ambulatory patients that have daily radiotherapy in HUG
- No risk of swallowing the mouth wash solution (determined before inclusion by a recovery of more than 90% of the 15ml of water solution used for testing)
- Treatment with chemo- and/or radiotherapy causing oral mucositis
- Oral pain associated with mucosal injury (WHO grading of mucositis \>= 2)
- Cognition: Mini Mental Status Examination of at least 28/30
Exclusion
Key Trial Info
Start Date :
December 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2008
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00613743
Start Date
December 1 2007
End Date
December 1 2008
Last Update
January 13 2010
Active Locations (1)
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1
University Hospital Geneva
Geneva, Collonge-bellerive, Switzerland, 1245